User profiles for Danielle Stewart

Daniel C. Stewart, Ph.D.

University of Pennsylvania
Verified email at vet.upenn.edu
Cited by 747

[HTML][HTML] Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene

J Alam, D Stewart, C Touchard, S Boinapally… - Journal of Biological …, 1999 - ASBMB
Stress response elements, which mediate induction of the mouse heme oxygenase-1 (HO-1)
gene by several agents, resemble the binding site for the activator protein-1 (Jun/Fos), Maf, …

White matter changes in schizophrenia: evidence for myelin-related dysfunction

KL Davis, DG Stewart, JI Friedman… - Archives of general …, 2003 - jamanetwork.com
Numerous lines of inquiry implicate connectivity as a central abnormality in schizophrenia.
Myelination and factors that affect myelination, such as the function of oligodendroglia, are …

[HTML][HTML] Degradation of transcription factor Nrf2 via the ubiquitin-proteasome pathway and stabilization by cadmium

D Stewart, E Killeen, R Naquin, S Alam… - Journal of Biological …, 2003 - ASBMB
Nrf2 mediates inducer-dependent activation of the heme oxygenase-1 (HO-1) gene (Alam, J.,
Stewart, D., Touchard, C., Boinapally, S., Choi, AM, and Cook, JL (1999) J. Biol. Chem.274, …

[HTML][HTML] Identification of activating transcription factor 4 (ATF4) as an Nrf2-interacting protein: implication for heme oxygenase-1 gene regulation

CH He, P Gong, B Hu, D Stewart, ME Choi… - Journal of biological …, 2001 - ASBMB
Nrf2 regulates expression of genes encoding enzymes with antioxidant (eg. heme oxygenase-1
(HO-1)) or xenobiotic detoxification (eg. NAD(P)H:quinone oxidoreductase, glutathione S…

Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration

RM Perciavalle, DP Stewart, B Koss, J Lynch… - Nature cell …, 2012 - nature.com
MCL-1, an anti-apoptotic BCL-2 family member that is essential for the survival of multiple
cell lineages, is also among the most highly amplified genes in cancer. Although MCL-1 is …

Hypertension-linked pathophysiological alterations in the gut

…, CT Cole-Jeffrey, GO Lobaton, DC Stewart… - Circulation …, 2017 - Am Heart Assoc
Rationale: Sympathetic nervous system control of inflammation plays a central role in
hypertension. The gut receives significant sympathetic innervation, is densely populated with a …

[HTML][HTML] Mechanism of heme oxygenase-1 gene activation by cadmium in MCF-7 mammary epithelial cells: role of p38 kinase and Nrf2 transcription factor

J Alam, C Wicks, D Stewart, P Gong, C Touchard… - Journal of Biological …, 2000 - ASBMB
The mouse heme oxygenase-1 (HO-1) gene,ho-1, contains two inducible enhancers, E1 and
E2. Of several cell lines tested, induction of an E1/luciferase fusion construct, pE1-luc, by …

Coupling assembly of the E-cadherin/β-catenin complex to efficient endoplasmic reticulum exit and basal-lateral membrane targeting of E-cadherin in polarized MDCK …

YT Chen, DB Stewart, WJ Nelson - The Journal of cell biology, 1999 - rupress.org
The E-cadherin/catenin complex regulates Ca ++ -dependent cell–cell adhesion and is
localized to the basal-lateral membrane of polarized epithelial cells. Little is known about …

A 12-week study of tacrolimus ointment for the treatment of atopic dermatitis in pediatric patients

A Paller, LF Eichenfield, DYM Leung, D Stewart… - Journal of the American …, 2001 - Elsevier
The safety and efficacy of 0.03% and 0.1% tacrolimus ointment for the treatment of atopic
dermatitis were evaluated in a 12-week, randomized, double-blind, vehicle-controlled study of …

Photodynamic therapy with topical methyl aminolevulinate for actinic keratosis: results of a prospective randomized multicenter trial

DM Pariser, NJ Lowe, DM Stewart, MT Jarratt… - Journal of the American …, 2003 - Elsevier
Background: Photodynamic therapy (PDT) is a promising new treatment modality for actinic
keratoses. Methyl aminolevulinate (MAL) (Metvix, PhotoCure, Oslo, Norway) leads to …